The adverse events were: most commonly nasopharyngitis, influenza, upper respiratory tract infection, and headache -- over a median 4.1 years of follow-up.
Guess who is susceptible to Coronavirus?
"Adults are also more susceptible to a detrimental immune response that causes a condition called acute respiratory distress syndrome (ARDS)," said Dr. James Cherry, a professor of pediatrics and infectious diseases at UCLA's Geffen School of Medicine. "A complicated imbalance of immune cell activity sends inflammation in the lungs into overdrive, ultimately causing fluid to fill the alveoli, or air sacs, according to research published in the journal Annals of Translational Medicine."
Severe Adverse Events: 9% were: Neurocognitive events were defined using Medical Dictionary for Regulatory Activities high-level group terms of deliria, cognitive and attentive disorders and disturbances, dementia and amnestic conditions, disturbances in thinking and perception, and mental impairment disorders.
Keep in mind, this study was done on relatively young people - average age of 34 in one group and 55 in the 2nd group.
They don't really discuss a benefit other than LDL lowering! This isn't right. Here is there "study limitation:"
The limitations of this study include the lack of a control arm, the lack of blinding, and the earlier than planned termination of the trial and hence small number of patients who could be assessed beyond 4 years. After the 4-year time point, the smaller patient numbers in both the HoFH and severe HeFH cohorts resulted in more variability in response.
Basic interpretation: Inconclusive if the drug had any impact on health other than the adverse events listed.
Make a good healthy choice - and it is NOT biologic drugs - ever.
If you are interested in determining your risk for Coronavirus consider taking this risk assessment and ordering our Chronic Disease Temperature blood tests. Each come with a consult that will dive into your risks and solutions to overcome these risks and also which risks to avoid - in general.
Thomas J. Lewis, Ph.D.