Updated: Aug 2
This radical new biomarker is the ferritin to iron ratio.
Watch the video to get the gist. This is first on this topic and more may follow.
Being an MIT scientists, I enjoy things that are a bit complicated. However, this is NOT complicated.
You want your ferritin to iron ratio to be in the range of 0.25 - 3.0 with the optimal being about 0.6.
Below, I go into what led me to this biomarker as documented in a book I wrote for an upcoming docu-series on Cancer produced by Jonathan Landsman of NaturalHealth365. If you sign up for the docu-series, you get my cancer book as an e-book, at no cost. I will let you know when you can sign up for the cancer series.
Biomarkers clearly predict future cancer, cancer prognosis, and overall cancer risk. The labs for the 2 cancer patients discussed in the previous chapter make this point very clearly. Just compare the white blood cell counts of the two individuals:
Is this not sufficient proof of cause and effect?
The most important biomarkers for cancer are the simplest, least expensive, and reflect innate immunity - your total white blood cell count, the differential of the white blood cells, and the neutrophil-to-lymphocyte ratio. Another profound marker for cancer, in general, and certainly based on the two examples, is ferritin.
Why ferritin? Because your brain is smart and knows if cancer or another infectious disease is brewing even if you are unsure. Here is my ferritin value during the height of my COVID-19 experience in December of 2021, when my internal temperature was around 103F.
Lewis' ferritin level during COVID-19: 1353 ng/mL; Iron was 14 ug/dL
Iron is a key component of hundreds of proteins and enzymes that support essential biological functions, such as oxygen transport, energy production, and DNA synthesis. Hemoglobin, myoglobin, cytochromes, and peroxidases require iron-containing heme as a prosthetic group for their biological activities. Because the body excretes very little iron, iron metabolism is tightly regulated. In particular, the iron regulatory hormone, hepcidin, blocks dietary iron absorption, promotes cellular iron sequestration and reduces iron bioavailability when body iron stores are sufficient to meet requirements.
Iron-containing enzymes are required for viruses, most likely including coronaviruses (CoVs), to complete their replication process. Moreover, poor prognosis occurred in the conditions of iron overload for patients upon infections of viruses. Most organisms require iron to replicate and thrive. The Georges Banks is the richest fishing ground in the world. The waters are murky due to prolific populations of microorganisms at the base of the food chain. Large iron reserves from the iron range of Minnesota and around Sorel, Canada dump iron into the St. Lawrence River ultimately feeding the Georges Banks with iron.
Some studies suggest "limiting iron represents a promising adjuvant strategy in treating viral infection through oral uptake or venous injection of iron chelators, or through the manipulation of the key iron regulators."[i] However, your body is way ahead of this "cutting edge" research. It is called "anemia of chronic inflammation." In reality, it is anemia of chronic infection. This syndrome has many names. The definition by the National Institutes of Health is: "Anemia of inflammation, also called anemia of chronic disease or ACD, is a type of anemia that affects people who have conditions that cause inflammation, such as infections, autoimmune diseases, cancer, and chronic kidney disease (CKD)."
Simply put, your brain recognizes that pathogens need iron to replicate. The body does not have a robust system to shed iron, but it does have a convenient iron storage protein called ferritin. When a virulent pathogen is detected by your immune system, signals are sent to sequester excess iron in ferritin. Arguably more important, but less studied compared to ferritin itself is the ferritin to free iron (or just iron) ratio. Let's look at the iron and ferritin values for the 3 individuals - myself included:
The ferritin to iron ratio may seem inconsistent with the outcomes. That is, the man with cancer died yet his ratio was the lowest. However, the ratio reflects the current acute state of the disease. The man had slowly developed cancer and a myriad of other chronic conditions. The lady, based on her symptoms at the time of the blood draw, was much sicker compared to the man. I had a severe case of acute COVID-19 and struggled to get myself to the lab. In this sense, the ratios were quite accurate at characterizing each of our states of health at the time of the measurement.
You still may disagree that cancer is an infectious disease. However, what cannot be argued is the similar way in which our bodies respond to cancer and a virus like SARS-CoV-2. However, the definition of anemia of chronic inflammation implicates infection. Inflammation is almost always caused by an infectious process. Either way, iron labs can be extraordinarily predictive.
[i] Liu W, Zhang S, Nekhai S, Liu S. Depriving Iron Supply to the Virus Represents a Promising Adjuvant Therapeutic Against Viral Survival. Curr Clin Microbiol Rep. 2020;7(2):13-19. doi:10.1007/s40588-020-00140-w
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