Peptides: No Free Lunch!
- Dr. Thomas J. Lewis
- 9 minutes ago
- 6 min read
Taking a combination of peptides for weight loss and muscle building can be a disaster!
Start watching/listening at 38:48
This is a talk by Dr. William Seeds titled, "Creatine, Peptides & Bioregulators: Separating Hype From Truth w/ Dr William Seeds | Mind Pump 2667"
In this segment, Dr. Seeds discusses various peptides, including Myostatin inhibitors.
Here is the AI Summary.
Myostatin Inhibitors: Health Implications
The discussion focused on the implications of myostatin inhibitors, highlighting that while they can significantly increase muscle mass, the resulting muscle may be inefficient and potentially harmful. The speakers explained that natural muscle growth, achieved through exercise, is linked to improved mitochondrial function and overall health benefits, unlike the muscle gained through myostatin inhibition, which lacks these advantages. They emphasized that strength, rather than muscle size, is a stronger indicator of health and longevity.
Benefits of Glycolytic Muscle Conversion
The discussion focused on the implications of building more glycolytic muscle through cellular medicine, which leads to inefficient muscle that can cause insulin resistance and obesity. The doctor explained that training to convert type 2B fibers to type 2A fibers, which increases mitochondria and endurance, is more beneficial than building glycolytic muscle. They also discussed how myostatin inhibition depletes satellite cells, which are crucial for muscle repair and renewal, potentially leading to increased injuries and reduced training response. The conversation concluded with concerns about the long-term effects of artificial muscle growth on mitochondrial function and cancer risk.
Myostatin Inhibitor Health Risks
The discussion focused on the potential risks and limitations of myostatin inhibitors, which can increase muscle mass but may also lead to negative health outcomes such as insulin resistance, reduced VO2 max, and increased cancer risk due to cell senescence. The doctor expressed concerns about the current interest in these compounds, particularly in combination with activin A inhibitors, noting that they could disrupt normal metabolic processes and lead to unhealthy muscle growth. They emphasized that while these treatments might initially seem beneficial, the long-term health implications are concerning, and more research is needed to fully understand the potential risks.
GLP-1 Agonists in Bodybuilding
The discussion focused on various GLP-1 agonists, including terzepatide and the triple agonist ratitutide, which combines GLP-1, GIP, and glucagon. The doctor explained that ratitutide's addition of glucagon could help prevent muscle wasting and improve cell efficiency, particularly during training. They also discussed the use of these drugs in the bodybuilding community, noting that bodybuilders were reporting better energy and reduced water retention while using smaller doses. The conversation concluded with a critical assessment of bioregulators, which the doctor dismissed as a marketing ploy, noting that only a few peptides like BPC157 can effectively be taken orally due to their resistance to stomach enzymes.
With that information in hand, I FIRMLY believe that peptides that support immunity are very useful, particularly the thymosins - see below.
Here is the video and summary from my talk on "Why You Die." I make the point that the major driver of aging and premature aging is immunosenescence and decline in regulatory substances - hormones and peptides. The peptides produced by the thymus gland - thymosin alpha 1 (TA1) and thymosin beta 4 (TB4) are among the most studied and safest peptides currently investigated and understood.
You can source peptides yourself. However, we are offering a "needs evaluation" program and access to a highly reliable, proven source of these peptides. Keep in mind that peptides are NOT a silver bullet. Have you optimized the big 3?
Nutrition
Exercise
Sleep
Fix these before considering the crutch of peptides.
But... these peptides have been proven to combat infections and cancers when the big 3 are NOT enough.
Here is our offer.
15-minute consult with Dr. Lewis
Consult with Inga Savage, who will provide additional advice and get you peptides.
Thymosins sourced for you (at your cost)
We are doing this for the next couple of months for $195. Contact Jodi if interested at jlaird@healthrevivalpartners.com
If the above HTML link to the video does not work, use this...
Auto-Generated Summary of the Presentation:
Summary
Vitamin D and Peptide Research
The discussion focused on vitamin D supplementation, with Michael explaining that most people need 2,500-5,000 IUs daily due to low sun exposure, and Dr. Lewis recommending cod liver oil as a source of different vitamin D versions. They discussed magnesium supplements, with Dr. Lewis preferring magnesium chloride for its higher elemental magnesium content compared to other forms. The conversation concluded with Dr. Lewis introducing a presentation on peptides and aging, mentioning his collaboration with Dr. Carter and a 5-minute clip from Ryan Smith of True Diagnostics regarding aging clocks, while noting concerns about peptides that would be addressed later in the presentation.
Peptides and Healthy Aging Strategies
The discussion focused on the role of peptides as an adjuvant to healthy behaviors, emphasizing that healthy behaviors are more important than peptides for longevity. Dr. Trump highlighted the importance of exercise, particularly weight-bearing exercises, in maintaining muscle mass and overall health, contrasting with the common advice to reduce activity due to age-related concerns. He stressed that aging is not primarily caused by muscle mass loss but by a decline in the body's ability to repair itself, and he encouraged maintaining an active lifestyle to support immune function and longevity.
Aging and Longevity: Lifestyle Factors
The doctor discussed the effects of aging on various physiological systems, noting that while sensory perception and nervous system efficiency decline, these do not significantly impact longevity. They highlighted that many people in Japan live beyond 100 years with full cognitive function, suggesting that lifestyle factors may play a crucial role in preventing a "cliff" decline in later life. The doctor also emphasized the importance of movement, blood flow to the brain, and proper nutrition, particularly mentioning the Japanese practice of portion control and the role of LDL in vessel repair. They concluded that while there is a gradual failure in body systems with age, this is often due to societal and medical failures rather than an inherent biological process.
Immunosenescence and Aging Insights
The doctor discussed the relationship between aging and immunosenescence, explaining how the immune system gradually declines with age and contributes to chronic inflammation and susceptibility to age-related diseases. They compared aging to the decline of old cars, emphasizing that proper care can extend lifespan and improve health. The doctor highlighted the importance of maintaining a robust immune system and suggested that treatments for conditions like dry eye and skin wrinkling might be related, as they target similar underlying issues. They also criticized the focus on numerous disease codes in medical systems, arguing that chronic disease is primarily a result of imbalanced repair and deterioration pathways.
LDL and Longevity Factors
Dr. discussed the importance of LDL in the body's repair mechanisms, highlighting its role in delivering repair molecules and plasmalogens. He introduced the AMIS acronym to categorize factors affecting longevity, including autophagy, micronutrient status, infections, stress, and sensitivity. Dr. also explained the decline in immune function with age, particularly the shrinking of the thymus gland, which affects the body's ability to produce new immune cells and respond to pathogens effectively. He suggested that maintaining a healthy lifestyle, including proper nutrition and exercise, can support immune function and repair pathways.
Microbial Roles in Human Aging
The doctor discussed the roles of microorganisms in the human body, including mutualism, commensalism, and parasitism. He explained how microorganisms contribute to aging and death, and how a less diverse microbiome can lead to immunosenescence and age-related diseases. The doctor also mentioned the concept of a "necrobiome" and posed the question of whether death could be a continuum in the eyes of microorganisms. He suggested that microorganisms can start the decomposition process before death, which he referred to as chronic disease.
Dental Infections and Immune Response
Dr. discussed the potential dangers of untreated dental infections, comparing them to septic toes and explaining how they can trigger responses from endogenous microbes. He emphasized the importance of understanding chronic diseases and their long incubation periods, often linked to micronutrient deficiencies. Dr. also touched on the hygiene hypothesis, suggesting that some exposure to pathogens can actually strengthen the immune system, and mentioned the example of H. pylori, a common infection that many people carry asymptomatically.
Thymus and Immune System Function
The discussion focused on the thymus gland's role in immunity, particularly its function in maturing T cells and supporting the immune system. The doctor explained that the thymus naturally shrinks with age, leading to immunosenescence, and suggested that exogenous administration of thymosin peptides could help compensate for this decline. They also mentioned that thymosin beta-4 has more general roles, such as regulating cell cytoskeleton and promoting wound healing. The conversation concluded with a brief mention of peptide therapy and its potential benefits for anti-aging and regenerative therapies.
Peptide Therapy for Immune Support
The meeting focused on the study and application of peptides, particularly Thymosin Beta 4, in health and longevity. Dr. Michael Carter, an expert in peptides, discussed their potential benefits, emphasizing their role in immune function and their safety, despite limited testing for combinations and levels. He highlighted the importance of foundational health practices, such as diet and detoxification, before considering peptide therapy. The discussion also touched on delivery methods, the challenges of measuring peptide levels, and the need for further research. Dr. Carter recommended working with experts like Dr. Michael to explore peptide therapy options, particularly for immune support.
Stay Well. Thomas J. Lewis, Ph.D.
