Generics come from China and India.
According to Bloomberg, "An FDA quality-control nightmare reveals how impurities end up in America's blood pressure pills.
Do you think contaminants in generic drugs is the issue that should be of greatest concern to you?
Read in Bloomberg Businessweek: https://apple.news/AXVsCEhUBQpWb7iGV121XQA
The drug in question is the blood pressure drug, Valsartan which is a type of blood pressure-reducing medication (angiotensin-converting enzyme inhibitor - ARB)
Let's look at the value of this drug, independent of the generic contamination issue:
1. These drugs don't do much for you. Here is a 2017 medical research paper titled,
Angiotensin Receptor Blockers Do Not Reduce Risk of Myocardial Infarction, Cardiovascular Death, or Total Mortality: Further Evidence for the ARB-MI Paradox
Here is the summary:
A systematic review/meta-analysis conducted demonstrated that in 20 trials of ARB (Valsartan and other BP meds in this class) versus placebo (66,282 people in the studies, 21 studies) ARB DID NOT improve all-cause mortality. Furthermore, when the trials were analyzed in combination, the impact of ARB on mortality was precisely zero compared with placebo and virtually zero compared with an active comparator.
Placebo-controlled trials are the most rigorous method of assessing treatment efficacy (as well as harm), and, consequently, it is concerning that other meta-analyses of ARBs versus placebo-controlled trials have also reported a lack of mortality reduction in patients with high risk, those with diabetes mellitus, and patients with hypertension as well as no reduction in heart attack or cardiovascular mortality.
Please re-read until you are sure you got the message which is:
...No benefit from taking these drugs...
Downside of Valsartan and ARBs to lower blood pressure:
Common side effects include:
headache, dizziness, lightheadedness, tiredness, flu symptoms, upper respiratory infection, diarrhea, cold symptoms (cough, runny or stuffy nose, sneezing, sore throat), sinusitis, nausea, stomach pain, swelling, blurred vision, itching or skin rash, back pain, and joint pain.
Serious side effects of include: