Summary:
Lowering LDL causes strokes
Statins lower LDL
Statins cause strokes
The increase in strokes is very high - at least 270% or more depending upon your LDL level
A stroke is a cardiovascular event. Statin drugs cause strokes.
Is your "total cholesterol" 230 mg/dL? If not, get off "cholesterol" lowering drugs or increase cholesterol and fat intake.
Abstract
Objective
To prospectively examine the association between low-density lipoprotein (LDL) cholesterol (LDL-C) concentrations and intracerebral hemorrhage (ICH) risk.
Methods
The current cohort study included 96,043 participants (mean age 51.3 years) who were free of stroke, myocardial infarction, and cancer at baseline (2006). Serum LDL-C concentrations were assessed in 2006, 2008, 2010, and 2012. Cumulative average LDL-C concentrations were calculated from all available LDL-C data during that period. Incident ICH was confirmed by review of medical records.
Results
We identified 753 incident ICH cases during 9 years of follow-up.
The ICH (stroke) risk was similar among participants with LDL concentrations of 70 to 99 mg/dL and those with LDL-C concentrations ≥100 mg/dL.
LEWIS COMMENT: They did NOT compare an LDL in the range of 100-130 with an LDL of 140 - so we do not know if the risk is higher in the 100-130 range compared to 140, but we can guess it is based on this data.
In contrast, participants with LDL-C concentrations <70 mg/dL had a significantly higher risk of developing ICH than those with LDL-C concentrations of 70 to 99 mg/dL;
adjusted hazard ratios were 1.65 - THAT MEANS A 65% HIGHER RISK - (95% confidence interval [CI] 1.32–2.05)
for LDL-C concentrations of 50 to 69 mg/dL and 2.69 (95% CI 2.03–3.57) for LDL-C concentrations <50 mg/dL.
THIS IS A 270 INCREASE IN STROKE RISK.
Conclusions
We observed a significant association between lower LDL-C and higher risk of ICH when LDL-C was <70 mg/dL and the association became nonsignificant when LDL-C ≥70 mg/dL. These data can help determine the ideal LDL range in patients who are at increased risk of both atherosclerotic disease and hemorrhagic stroke and guide the planning of future lipid-lowering studies.
THE REAL CONCLUSION IS THAT STATINS CAUSE VASCULAR DAMAGE THAT LEADS TO STROKES. ANY ARTIFICIAL LOWERING OF "CHOLESTEROL" (LDL) INCREASES STROKE RISK.
FINAL CONCLUSION: STATINS DRUGS CAUSE CARDIOVASCULAR DISEASE.
Here is the link to the entire paper. Note that this paper is published in the TOP neurology journal. Shouldn't neurologists and cardiologists compare notes?
Index & Upcoming (short) blogs on cholesterol and statins
Number 1: Cholesterol fun (true) facts - completed
Number 2: Is the actual cholesterol molecule important? c - completed
Number 3: What is an optimal TC value? Remember, no one knows their actual cholesterol molecule value. - completed
Number 4: Surprising fact about cholesterol as an antibiotic - completed
Number 5: TC simple math - dumb doctors - completed
Number 6: What is LDL really? - completed
Number 7: Statins - do they lower the cholesterol molecule? - completed
Number 8: What did we learn from the new "biologics" to lower "cholesterol" - completed
Number 9: Niacin and other "cholesterol" management treatments - completed
Number 10: What did Natasha Campbell-McBride say about cholesterol/lipids? - completed
Number 11: What is a QALY, and how does it relate to "cholesterol"? - completed
Number 12: Idiot doctor from Johns Hopkins, Roger Blumenthal - completed
Number 13: Statins cause Alzheimer's and ALS - THEHIGHWIRE - completed
Number 14: Statin drugs CAUSE diabetes - completed
Number 15: The statin merry-go-round to poor cardiovascular outcomes - completed
Number 16: How statins CAUSE heart disease - completed
Number 17: How statins CAUSE heart disease - part 2 - completed
Number 18: Women and statin drugs - completed
Number 19: If not "cholesterol," then what? - completed
Number 20: If not "cholesterol," then what? - part 2 - completed
Number 21: Statins and erectile dysfunction - completed
Number 22: Who says statins do NOT extend life? - completed
Number 23: Statins cause strokes.
Number 24: Statins & Cholesterol Summary
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Ideal example of a Total Cholesterol formula you presented.
LDL 140 mg/dL
HDL 70 mg/dL
Triglycerides 50 mg/dL (20% is 10)
Total Cholesterol = 140 + 70 + 10 = 220… I get the impression 220 to 230 is ideal?
My Total Cholesterol = 193 + 67 + 15 = 275… How high is too high? Is 275 still ideal?